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Vertex Pharmaceuticals, Inc.

VRTX

Market Cap$103.4B

Close$

Compare to Similar Companies

	P/E Ratio	Dividends	Return on Equity	Price-to-Sales	Debt-to-Equity
Vertex Pharmaceuticals, Inc.	28.5	-	21%	9.2	0.1

Earnings Call Q2 2025

August 4, 2025 - AI Summary

Robust Revenue Growth: Vertex Pharmaceuticals reported Q2 2025 revenue of $2.96 billion, a 12% increase year-over-year. The growth was driven by increasing patient demand for CF therapies, particularly the newly launched ALYFTREK (boasting a lower royalty burden compared to its predecessor TRIKAFTA) and ongoing contributions from CASGEVY and JOURNAVX.

Diverse Product Pipeline: Vertex is expanding its product portfolio with key launches in cystic fibrosis, sickle cell disease, and acute pain management. The company is particularly focused on gaining a DPN indication for suzetrigine following discussions with the FDA, though broader PNP indications remain a future goal. This presents opportunities for expansion across various pain treatments.

Challenges in Pain Management: Despite progress, the FDA has indicated that there is no current path for a broad PNP label for suzetrigine. This could limit market opportunities in a category with significant unmet needs. Vertex will focus on solidifying DPN first before exploring broader indications like small fiber neuropathy.

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$477.63

Target Price by Analysts

18.5% upsideVertex Pharmaceuticals Target Price Details

$649.11

Current Fair Value

61% upside

Undervalued by 61% based on the discounted cash flow analysis.

Share Statistics

Market cap	$103.40 Billion
Enterprise Value	$98.55 Billion
Dividend Yield	$- (-)
Earnings per Share	$-2.08
Beta	0.43
Outstanding Shares	256,700,000

Return

Return on Equity	-
Return on Assets	-
Return on Invested Capital	-

Valuation & Multiples

P/E Ratio	28.46
PEG	-22.11
Price to Sales	9.16
Price to Book Ratio	6.11
Enterprise Value to Revenue	8.63
Enterprise Value to EBIT	23.37
Enterprise Value to Net Income	27
Total Debt to Enterprise	0.02
Debt to Equity	0.09

Revenue Sources

No data

Insider Trades

ESG Score

No data

About Vertex Pharmaceuticals, Inc.

CEO: Jeffrey Leiden

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